Thermodynamics for Biological Systems : Classical and Statistical Aspect

Course Duration : 12 Weeks

@VTU COE

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What you will learn

  • Biotechnology and Bioengineering

Thermodynamics is one of the essential tools to analyze biological systems. Thus, it is essential that an undergraduate in biological engineering knows the relevant thermodynamics principles. Classical thermodynamics is suitable for analysis in the continuum domain, whereas when the number of molecules per cell is less than say 100, the principles of classical thermodynamics are invalid for that species. However, the principles of statistical thermodynamics can be used to analyze such situations, and other situations too. Therefore, this course will cover both classical and statistical aspects to provide a complete set of tools to a biological engineer to thermodynamically analyze bio-systems. Such an analysis will help in manipulation and design of bio-systems.

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Equations for a Closed System
Preview 17:04
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Chemical Potential
Preview 17:29
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Gibbs Duhem equation
Preview 08:45
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Maxwell's relations
Preview 34:44
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Inter-relationships between thermodynamic variables contd
Preview 09:17
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Some useful mathematical manipulations
Preview 20:39

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Thermodynamic relations for a closed system with 1 mole of pure substance
Preview 16:57
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Maximum work
Preview 11:05
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Open systems
Preview 35:38
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Equations of state - virial equations
Preview 23:10
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Equations of state - cubic equations
Preview 19:39
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Volume estimation
Preview 18:31
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Volume estimation, contd
Preview 08:48

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Generalized correlations
Preview 21:31
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Generalized correlations (contd)
Preview 09:48
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Residual properties
Preview 10:16
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Residual properties contd.
Preview 32:27
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Generalized correlations and residual properties
Preview 18:22
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Fugacity coefficient estimation
Preview 27:06
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Review of module 3
Preview 42:47

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Learning aspects
Preview 09:20
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Chemical potential formulations
Preview 34:57
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Lewis and Randall rule
Preview 15:32
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Partial molar properties
Preview 13:53
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Partial molar property estimation from mixing experiments
Preview 24:54
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Partial molar property estimation (contd.)
Preview 18:34

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Activity coefficient from excess property
Preview 19:56
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Activity coefficient from excess property (contd.)
Preview 22:31
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Models for activity coefficient in a binary system
Preview 16:42
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Models for activity coefficient for a binary system (contd.)
Preview 17:42
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Review of module 4
Preview 40:00
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Criteria for phase equilibrium
Preview 15:31
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Phase rule for non-reacting systems
Preview 11:51

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Clausius Clayperon equation
Preview 13:04
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Clausius Clayperon equation (contd.)
Preview 24:53
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Vapour liquid equilibrium
Preview 27:09
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Vapour-liquid equilibrium (contd.)
Preview 09:08
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Estimation of fugacity coefficient from P-V-T data at equilibrium
Preview 12:02
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Liquid-liquid and solid-liquid equilibria
Preview 17:11
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Review of module 5
Preview 36:24
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Criteria for bioreaction equilibria
Preview 24:27
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Phase rule for reacting biosystems
Preview 07:22

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Equilibrium constants
Preview 12:48
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Effect of temperature on the equilibrium constants
Preview 18:20
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Reaction in liquid or solid phases
Preview 22:05
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Free energy changes for some bioreactions
Preview 16:51
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Electrolytes
Preview 43:07
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Review of the classical thermodynamics part
Preview 50:34

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Introduction to Statistical thermodynamics
Preview 10:12
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Concepts of macro and microstates
Preview 17:04
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Thermodynamic probability
Preview 02:42
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Boltzmann distribution law
Preview 19:58
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Defining β in Boltzmann distribution law
Preview 24:53
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Relationship between partition function and thermodynamic quantities
Preview 14:21
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Partition function of mono atomic gases
Preview 31:11
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Entropy in terms of probablity
Preview 08:36
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Gibbs paradox
Preview 10:27

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Thermodynamic probability for distinguishable particles
Preview 22:10
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Thermodynamic probability for indistinguishable particles
Preview 19:52
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Sackur - Tetrode equation
Preview 10:23
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Partition function and Helmholtz and Gibbs free energy
Preview 13:21
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Ensemble approach
Preview 15:17
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Ensemble average, time average, Ergodic hypothesis
Preview 12:48
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Partition function for classical systems
Preview 22:32

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Pair potentials for atomic systems
Preview 33:30
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Potential for molecular systems
Preview 22:01
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Computer code for LJ potential
Preview 13:52
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Introduction to computer simulations
Preview 11:09
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Computer simulations of macromolecules
Preview 09:53
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MD simulation examples
Preview 21:00
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Link between theory and experiments
Preview 06:44
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MD protocol
Preview 23:20
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Computer simulation tricks
Preview 27:17

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Understanding force fields
Preview 22:25
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Idea of Z-matrix
Preview 10:37
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Basics of MD simulations
Preview 20:13
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Integration algorithms
Preview 14:59
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Calculation of Columbic force
Preview 08:17
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Calculation of LJ force
Preview 11:01
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Monte Carlo simulations
Preview 16:01
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Analysis of MD trajectory
Preview 08:34
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Case study (water)
Preview 15:24
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Case study (water)
Preview 15:24
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Meet Your Instructor
@VTU COE
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Instructor
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40 Students
718 Courses
About Instructor

VTU is one of the largest Technological Universities in India with 24 years of Tradition of excellence in Engineering & Technical Education, Research and Innovations. It came into existence in the year 1998 to cater the needs of Indian industries for trained technical manpower with practical experience and sound theoretical knowledge.

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Free

  • Course Duration
    27 h 42 m 56 s
  • Course Level
    Intermediate
  • Student Enrolled
    0
  • Language
    English
This Course Includes
  • 27 h 42 m 56 s Video Lectures
  • 0 Quizzes
  • 0 Assignments
  • 0 Downloadable Resources
  • Full Lifetime Access
  • Certificate of Completion